Bioactivity-Directed Isolation of Anticancer Constituents from Underexplored Folklore: <i>Rhus punjabensis</i> Stewart.

ABSTRACT:

Background

Medicinal plants continue to offer a promising source of novel bioactive compounds for cancer therapy due to their affordability, biocompatibility, and low toxicity. Rhus punjabensis Stewart, an ethnomedicinal species from the family Anacardiaceae, has long been used in the traditional medicine of northern Pakistan to treat inflammatory, hepatic, and infectious diseases. However, its phytochemical composition and anticancer potential remain largely unexplored.

Methods

This study employed a bioactivity-guided isolation strategy to identify and characterize anticancer constituents from R. punjabensis leaves. The plant material was sequentially fractionated using solvents of increasing polarity, followed by purification via column chromatography. Each f

SUBMITTER: Tabassum S 

PROVIDER: S-EPMC12655016 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature