Targeted Metabolomic Analysis Reveals Solvent-Dependent Phenolic Variation and Associated Antioxidant and Antibacterial Activity in Coriander Seeds (<i>Coriandrum sativum</i> L.).

ABSTRACT: Coriandrum sativum L. (coriander) seeds have long been used as a traditional medicine and a spice worldwide. Despite its abundant use, bioactive properties of coriander seeds, correlated with the antioxidant and phenolic data, have not been fully studied systematically. This study evaluated the phenolic data, antioxidant capacity, and antibacterial activity of coriander seed extracts obtained using solvents of differing polarity. Higher total phenolic content (TPC) and antioxidant activity were observed in the polar extracts, while moderate and non-polar extracts possessed higher antibacterial activity. Acetone extract (Ace) had the highest antibacterial activity, with an inhibition zone diameter (IZD) of 16.2 ± 0.2 mm against B. subtilis, and a minimum inhibitory concentrati

SUBMITTER: Ekanayake CP 

PROVIDER: S-EPMC12655154 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature