Vision-Related Quality of Life in Patients with Optic Neuropathy: Insights from a Portuguese Single Center Using the NEI-VFQ-25.

ABSTRACT: Background/Objectives: Optic neuropathies (ON) are a clinically heterogeneous group of disorders that can cause profound and lasting visual disability, with wide-ranging effects on patients' quality of life. Although the NEI-VFQ-25 is an instrument for assessing vision-related quality of life (VRQoL), few studies have systematically compared patient-reported outcomes across multiple ON subtypes, especially in underrepresented populations. We aimed to delineate how etiological differences and longitudinal visual acuity trajectories shape VRQoL in a diverse Portuguese cohort with ON. Methods: This retrospective, cross-sectional study included 152 patients diagnosed with ON and followed at São João University Hospital, Portugal. All participants completed the validated NEI-VFQ-2

SUBMITTER: Bezerra S 

PROVIDER: S-EPMC12655186 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature