Antiproliferative Potential of Cobalt(II) Phenanthroline Complexes with Pyridonates.

ABSTRACT: The reaction of CoCl₂ · 6H₂O with 6-chloro-2-hydroxypyridine (Hchp) and 1,10-phenanthroline (phen) afforded the complex [Co(chp)₂(phen)] (1). Although this complex has been previously reported, it was obtained in this work under mild conditions (in acetonitrile at room temperature) and characterized for the first time by single-crystal X-ray diffraction. The use of Co(F₃CCOO)₂ · 4H₂O under similar conditions yielded a new trinuclear molecular complex [Co₃(chp)₂(F₃CCOO)₄(phen)₂] (2). According to X-ray diffraction data, the cobalt(II) ions in complexes 1 and 2 are located in an octahedral environment (coordination number CN_Co = 6). A

SUBMITTER: Nikiforova ME 

PROVIDER: S-EPMC12655206 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature