Eighteen Years of Human Rhinovirus Surveillance in the Republic of Korea (2007-2024): Age- and Season-Specific Trends from a Single-Center Study with Public Health Implications.

ABSTRACT: Human rhinovirus (HRV) is the most common cause of upper respiratory tract infections and can cause substantial morbidity in children. Because its clinical features are nonspecific, differentiation from influenza virus and respiratory syncytial virus is often difficult, underscoring the diagnostic importance of real-time reverse transcriptase polymerase chain reaction (Real-Time RT-PCR)-based detection. This study aimed to characterize long-term epidemiological patterns of HRV in the Republic of Korea and assess their clinical and public health implications. We retrospectively analyzed 23,284 nasopharyngeal swab specimens collected between 2007 and 2024 from outpatients and inpatients presenting with influenza-like illness at a tertiary care hospital. HRV RNA was detected by Real-Time RT-P

SUBMITTER: Kim YJ 

PROVIDER: S-EPMC12655215 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature