Coaxial Electrospun Nanofibers of Shikonin and Cresol as Antibacterial Wound Dressing.

ABSTRACT: Background/Objectives: Skin wounds interrupt the natural anatomy and function of the skin. The body passes through four physiological phases to repair wounds after injury. Since the fibers are more closely related to the extracellular matrix structure, they can be used as scaffolds to accelerate wound closure. Shikonin is a botanical herbal remedy used as an anti-inflammatory agent and for its wound-healing characteristics. Cresols are known for their bactericidal and fungicidal properties, which promote their utilization as a disinfectant in soap. Therefore, this study aimed to formulate shikonin and cresol-loaded nanofibers for a dual wound-healing and antibacterial wound dressing in vitro. Methods: This study demonstrated the effectiveness of the drug-loaded nanofibers aga

SUBMITTER: Alsulaihem FM 

PROVIDER: S-EPMC12655277 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature