Dihydroquercetin in Weight Control: Systematic Review and Meta-Analysis of Preclinical Studies.

ABSTRACT: Background: Obesity is a global epidemic and a complex chronic disease affecting more than one billion patients, leading to severe health issues like diabetes, heart disease, and cancer. While lifestyle changes are the first-line treatment, they are often insufficient. Current medications may cause severe side effects, including muscle loss and vision problems. Objectives: This systematic review aims to generalize and evaluate data from preclinical studies on the effect of flavonoid dihydroquercetin (DHQ) on weight loss in experimental animals compared with placebo-treated animals. Methods: This systematic review was conducted in accordance with the PRISMA guidelines. The protocol was registered in the PROSPERO database in August 2025 (CRD420251129793). Risk of bias (R

SUBMITTER: Terekhov RP 

PROVIDER: S-EPMC12655469 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature