Anticancer Effects and Phytochemical Profile of <i>Lavandula stoechas</i>.

ABSTRACT: Background/Objectives:Lavandula stoechas has reported bioactivities, but its selective anticancer potential in human models remains insufficiently defined. This study aimed to compare cytotoxicity and selectivity of ethanol and methanol extracts prepared from fresh and dried L. stoechas and to profile candidate bioactive metabolites. Methods: Aerial parts Lavandula stoechas L. subsp. stoechas (L. stoechas L.) were extracted with ethanol or methanol from fresh (LsFE, LsFM) and dried (LsDE, LsDM) material. Cytotoxicity was assessed in cancer (MDA-MB-231, T98G, RT4) and non-malignant (hGF, ARPE-19) cells using Hoechst 33342-stained nuclear counts and MTS viability at 24-48 h. Metabolite identification was performed using LC-QTOF-MS in both posi

SUBMITTER: Sevim Nalkiran H 

PROVIDER: S-EPMC12655630 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature