Assessment of Estrogenic and Genotoxic Activity in Wastewater Using Planar Bioassays.

ABSTRACT: The contamination of ground and surface waters with micropollutants like estrogenic compounds and genotoxins is a major public health concern. Conventional wastewater treatment plants are currently not capable of completely removing those contaminants. In this study, we applied planar bioassays to investigate the genotoxicity and estrogenic activity of hospital and municipal wastewater from an Austrian treatment plant. Using the open-source 2LabsToGo platform in combination with the HPTLC-SOS-UmuC and HPTLC-YES assays, both genotoxic and estrogenic compound zones were detected in untreated wastewater. Genotoxic activity was found in sewage sludge filtrate and hospital wastewater, with bioanalytical concentrations ranging from 1.6 to 21.8 µg 4-NQO-EQ L^-1. Estrogenic responses wer

SUBMITTER: Windisch M 

PROVIDER: S-EPMC12656073 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature