From Safety Evaluation to Influencing Factors Analysis: A Comprehensive Investigation on Ocular Irritation of Baby Bath Products.

ABSTRACT: Given the underdevelopment and sensitivity of babies' eyes, frequently used baby bath products have garnered attention for their ocular irritation safety. The selection and application of raw materials are key factors. We tested 39 commercial baby bath products for ocular irritation safety and proposed a novel evaluation method using the "Risk Attention Index" to analyze formulation risk factors. The ocular irritation potential of 39 commonly used raw materials under typical usage conditions was investigated via animal and cell models. Results showed over 20% of commercial products had safety risks. Surfactants like cocamidopropyl betaine (CAPB), sodium laureth sulfate (SLES), and sodium lauroamphoacetate (SLA) had the highest "Risk Attention Index", requiring special attention. Some fragr

SUBMITTER: He Q 

PROVIDER: S-EPMC12656482 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature