Pharmacological Potential of Peruvian <i>Eustephia</i> Species (Amaryllidaceae): Alkaloid Diversity, Cholinesterase Inhibition, and Anti-<i>Trypanosoma cruzi</i> Activity.

ABSTRACT: The Amaryllidaceae family represents a prolific source of pharmacologically active compounds, boasting over 700 diverse alkaloids identified to date. However, the genus Eustephia (Amaryllidoideae subfamily) remains largely unexplored. This study focused on the alkaloid profiles and pharmacological potential of bulb and leaves extracts from three Peruvian Eustephia species (E. coccinea, E. darwinii, and E. hugoei). The phenolic and flavonoid levels as well as the antioxidant activity of the methanolic extracts, were determined. Twenty-six alkaloids were identified in the alkaloid-enriched extracts (AEEs). Homolycorine-type alkaloids predominated in E. darwinii and E. hugoei, whereas E. coccinea displayed greater chemical diversity show

SUBMITTER: Llalla-Cordova O 

PROVIDER: S-EPMC12656678 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature