Multidisciplinary Approach in Libman-Sacks Endocarditis.

ABSTRACT:

Background

Libman-Sacks endocarditis is a noninfectious form of endocarditis associated with systemic lupus erythematosus (SLE), antiphospholipid antibody syndrome (APS), and solid malignancies.

Case presentation

A 20-year-old woman with no medical history presented with left-sided weakness and facial drooping. Laboratory tests were unremarkable except for thrombocytopenia and a prolonged activated partial thromboplastin time. Brain magnetic resonance imaging revealed an acute ischemic infarct in the bilateral frontal lobes. A transthoracic echocardiogram (TTE) and subsequent transesophageal echocardiogram (TEE) identified two mitral vegetations with regurgitation: the first located on the posterior leaflet with perforation (1.2 × 1.0 cm) and the second (1.0 × 0.9 cm) situat

SUBMITTER: Satish V 

PROVIDER: S-EPMC12657074 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature