Fibrolipomatous hamartoma of the sciatic nerve: an atypical case report.

ABSTRACT: Fibrolipomatous hamartoma is a rare benign overgrowth of tissue consisting of intermixed adipose and fibrous connective tissue within the epineurium. However, involvement of the sciatic nerve is exceptionally rare. We present the case of a 46-year-old female who exhibited a progressively enlarging mass in her right posterior thigh, accompanied by sciatica and gluteal pain. Clinical assessment and MRI revealed a large lesion along the sciatic nerve with characteristic features of fibrolipomatous hamartoma. MRI findings demonstrated characteristic features, including isointense (to fat) on T1-weighted images and hyperintense with fat suppression on short tau inversion recovery sequences, indicating a sciatic nerve fibrolipomatous hamartoma. The diagnosis was histopathologically confirmed fol

SUBMITTER: Al Ghamdi YH 

PROVIDER: S-EPMC12657156 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature