Predictive performance of MRI and CT radiomics in predicting the response to induction chemotherapy in nasopharyngeal carcinoma: a network meta-analysis.

ABSTRACT:

Objectives

To evaluate the accuracy of different radiomics methods in predicting the response of nasopharyngeal carcinoma (NPC) to induction chemotherapy (IC).

Methods

A systematic search was conducted in PubMed, Embase, Web of Science, and Cochrane Library. Radiomics studies utilizing CT and MRI were included in this network meta-analysis. The quality of the studies was appraised via the PROBAST, RQS, and IBSI guidelines. The sensitivity, specificity, and accuracy of different radiomics models were analyzed.

Results

Ten eligible studies involving 1550 subjects were included. The pooled sensitivity and specificity of the radiomics models were 0.86 (95% CI: 0.78-0.91) and 0.69 (95% CI: 0.62-0.75), respectively. The AUC based on the SROC curve was 0.83 (95% CI: 0.70-0.9

SUBMITTER: Jian Y 

PROVIDER: S-EPMC12657194 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature