CMR T1 reactivity in healthy adult hearts: a systematic review and meta-analysis.

ABSTRACT:

Background

Cardiac stress T1-mapping is an advanced magnetic resonance imaging technique that enables the detection of myocardial ischemia and coronary microvascular dysfunction without the need for gadolinium-based contrast agents (GBCAs). This review seeks to synthesize reported mean ΔT1 values from studies involving healthy adults, establish an approximate range of myocardial T1 reactivity in this population, and explore factors underlying the heterogeneity observed across different studies.

Methods

PubMed, Web of Science, and Cochrane Central were searched for studies reporting myocardial T1 reactivity in healthy adult participants. The search strategy included terms such as: "Stress T1 'AND' Mapping" OR "Stress T1 'AND' Cardiovascular magnetic resonance" OR "Stress T1 '

SUBMITTER: Wang B 

PROVIDER: S-EPMC12657357 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature