Correlation of cognitive dysfunctions and diffusion tensor MRI measures in subjects with RRMS.

ABSTRACT:

Background

Cognitive dysfunction is a common impairment observed in individuals with Multiple Sclerosis (MS), affecting key domains such as attention, information processing speed, memory, and executive functions. This deficit is typically identified through comprehensive neuropsychological assessments, which represent the gold standard for cognitive evaluation. In recent years, increasing efforts have been made to integrate neuropsychological findings with advanced neuroimaging techniques to better understand the neural substrates of cognitive dysfunction. Among these, Diffusion Tensor Imaging (DTI) has emerged as a valuable tool for investigating microstructural changes in white matter (WM) that may underlie cognitive deficits in MS. However, despite its clinical utility, the pat

SUBMITTER: Mirabile A 

PROVIDER: S-EPMC12657435 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature