Relationship Between Complex Signal Identification and Non-Pulmonary Vein Foci.

ABSTRACT:

Background

Pulmonary vein isolation (PVI) is the cornerstone of atrial fibrillation (AF) ablation; however, recurrences often originate from non-pulmonary vein (non-PV) foci. The Complex Signal Identification (CSI) algorithm in CARTO 3 assigns electrogram-fractionation scores (0-10). This study evaluated the feasibility of CSI-assisted mapping for identifying non-PV triggers.

Methods

We retrospectively analyzed 23 consecutive patients undergoing first-time AF ablation between January and June 2024. After PVI, non-PV triggers were induced using isoproterenol and adenosine triphosphate (ATP). When ectopy was absent, rapid pacing during isoproterenol infusion followed by defibrillation was performed, and ATP testing was repeated. High-density CSI mapping was conducted during si

SUBMITTER: Kono H 

PROVIDER: S-EPMC12657636 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature