Plasma protein increase as a chronological aging factor in healthy toy poodles.

ABSTRACT: Although extensive research has examined aging markers in larger dog breeds, little is known about small breeds. This study assesses the relevance of aging biomarkers examined in larger breeds and other biological species, focusing on toy poodles (N = 40) as a model of small breeds and retrievers (N = 17) serving as a large-sized reference. Healthy individuals with no significant health declines for up to a year post-data collection were studied for age-related changes in various parameters, excluding disease factors. Our cross-sectional analysis identified significant correlations between age and increases in plasma protein concentration and amylase levels across both breeds, with breed-specific age-related declines in vaccine responses to various viruses observed only in toy poodles. Lon

SUBMITTER: Ozaki S 

PROVIDER: S-EPMC12657999 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature