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Transcranial static magnetic field stimulation of the primary motor cortex in essential tremor: a randomized pilot study.


ABSTRACT: Alterations in the motor cortex may contribute to essential tremor (ET) pathophysiology. Transcranial static magnetic field stimulation (tSMS), a non-invasive and portable technique, reduces corticospinal excitability, but its therapeutic potential for ET remains untested. This randomized, double-blind pilot study (clinicaltrials.gov#: NCT03780426, registered on December 19, 2018) investigated the acute effects of tSMS applied to the primary motor cortex in 27 ET patients (mean age: 66.9 ± 12.1 years). Patients received a 30-min tSMS session on either the left (n = 13) or right (n = 14) hemisphere. Postural tremor was assessed by accelerometry, and kinetic tremor by part B of the Clinical Rating Scale for Tremor. Twenty-three patients were included in the final analysis for primary and sec

SUBMITTER: Urso D 

PROVIDER: S-EPMC12658149 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature