Food-Herb Dual-Function in Astragali Radix-Poria-Rheum: Network Pharmacology and Database Mining for Diabetic Kidney Disease Mechanisms Exploration.

ABSTRACT: The growing demand for functional foods derived from medicinal-edible homologous resources offers a promising strategy to address the chronic metabolic dysregulation underlying diabetic kidney disease (DKD), particularly in patients requiring long-term pharmacological interventions. DKD, a metabolic disorder-driven complication of diabetes, is characterized by chronic hyperglycemia, insulin resistance (IR), and systemic metabolic dysregulation, necessitating novel dietary approaches to complement conventional therapies. To systematically explore the therapeutic potential of medicinal-edible homologous herbs in DKD management, this study retrieved clinical literature from the China National Knowledge Infrastructure (CNKI) database, focusing on traditional Chinese medicines (CHMs) with dual

SUBMITTER: Wang M 

PROVIDER: S-EPMC12658371 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature