Antenatal Corticosteroids and Bronchopulmonary Dysplasia in Very Preterm Infants.

ABSTRACT:

Importance

The impact of antenatal corticosteroids (ACS) on bronchopulmonary dysplasia (BPD) in very preterm infants remains controversial, with limited evidence on causal mediation pathways.

Objective

To evaluate the association between ACS and BPD in very preterm infants and assess whether respiratory distress syndrome (RDS) and invasive mechanical ventilation (IMV) have mediating roles.

Design, setting, and participants

This prospective multicenter cohort study included preterm infants from 28 tertiary centers in China between September 1, 2019, and December 31, 2020. Inclusion criteria were gestational age (GA) less than 30 weeks, admission to the neonatal intensive care unit with 24 hours of birth, and neonatal hospitalization for more than 2 weeks. Analysis was

SUBMITTER: Gao L 

PROVIDER: S-EPMC12658673 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature