Isolated Leptomeningeal Carcinomatosis in Triple-Negative Breast Cancer: A Case Report.

ABSTRACT:

Introduction

Leptomeningeal carcinomatosis (LC) is a rare but devastating complication that can arise from various cancers, particularly breast cancer.

Case presentation

We present the case of a female patient with early onset triple-negative breast cancer (TNBC) who developed isolated LC shortly after completing neoadjuvant and adjuvant treatment. The patient had no evidence of parenchymal brain metastases at the time of LC diagnosis. Our patient received treatment with both intrathecal and systemic chemotherapy. While there was a brief period of clinical improvement, she subsequently developed brain metastases and ultimately succumbed to its complications. Isolated LC is an extremely rare occurrence, as leptomeningeal metastasis usually presents concurrently with parenchym

SUBMITTER: Karaferi M 

PROVIDER: S-EPMC12659012 | biostudies-literature | 2025 Jan-Dec

REPOSITORIES: biostudies-literature