Ontology highlight
ABSTRACT: Background
The clinical significance of early postnatal ETCOc in the prediction of phototherapy (PT) for neonatal hyperbilirubinemia has not been fully characterized. We aimed to investigate the relationship between early postnatal ETCOc and the risk of PT within 7 days of life (7 DOLs) and diagnostic performance.Methods
This is a secondary analysis of the infants randomized to the control group of the HEME trial. Cases were infants who had PT within 7 DOLs and controls were infants who did not require PT. Multivariate logistic regressions were used for the analyses of phototherapy and early postnatal ETCOc, adjusting for transcutaneous bilirubin level, gestational age, birth weight, sex and maternal blood types. We also evaluated the predictive performance of ETCOc by comp
SUBMITTER: Yang G
PROVIDER: S-EPMC12659024 | biostudies-literature | 2025 Nov
REPOSITORIES: biostudies-literature