Correlation between white matter lesions and cognitive impairment after stroke.

ABSTRACT:

Introduction

This study examines the relationship between white matter lesions (WML) and vascular cognitive impairment in patients with acute ischemic stroke (AIS).

Materials and methods

We enrolled 120 AIS patients (79 males, 41 females; mean age 65.63 ± 10.12 years) admitted to the Department of Neurology, Mianyang Central Hospital, between February and November 2019. Demographic and clinical data were collected. All patients underwent cranial magnetic resonance imaging (MRI), and WML were graded using the Fazekas scale: mild WML (score 1-3, n = 67) and severe WML (score 4-6, n = 53). WML volume was quantified semi-automatically with 3D Slicer. Cognitive function was longitudinally assessed using the Clinical Dementia Rating (CDR) scale at two follow-up time points: 90 day

SUBMITTER: Zhang Y 

PROVIDER: S-EPMC12659025 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature