Evaluation of the relative benefits of FFR-guided, angiography-guided CR or culprit-only revascularization in patients with multivessel coronary disease: a systematic review and meta-analysis.

ABSTRACT:

Background

At present, the benefits associated with fractional flow reserve (FFR)-guided complete revascularization (CR) for instances of non-culprit stenosis in patients of coronary artery disease (CAD) affected by multivessel disease (MVD) remain poorly understood. This systematic review and meta-analysis was undertaken to clarify the cardiovascular benefits associated with FFR-guided and angiography-guided CR in patients with CAD and MVD.

Methods

The PubMed, Embase, and Cochrane databases were searched to locate randomized control trials (RCTs) comparing FFR-guided CR with angiography-guided CR or culprit-only percutaneous intervention (PCI). The primary outcome is major adverse cardiovascular events (MACE), as well as secondary outcomes were all-cause mortality, cardiac

SUBMITTER: Liu XY 

PROVIDER: S-EPMC12659027 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature