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Efficacy of S-1 Treatment in Recurrent and Metastatic Orbital Sebaceous Gland Carcinoma after Orbital Exenteration.


ABSTRACT:

Introduction

Herein, we report a case of recurrent and metastatic sebaceous gland carcinoma (SGC) following orbital exenteration, which was managed with S-1 administration.

Case presentation

The patient was a 78-year-old man. At the initial examination, the extension of SGC into the right orbit was noted, for which radiotherapy, instead of orbital exenteration, was administered as per patient preference. However, after 2 years, the tumor enlarged, necessitating right orbital exenteration. Six months after the procedure, recurrence with orbital apex involvement, invasion into the supraorbital wall, and metastasis to the right cervical lymph nodes were observed. Therefore, resection of the supraorbital wall and temporalis muscle skin valve and dissection of the right cervical

SUBMITTER: Yunoki T 

PROVIDER: S-EPMC12659166 | biostudies-literature | 2025 Jan-Dec

REPOSITORIES: biostudies-literature