Axillary Breast Cancer Masquerading as Extramammary Paget Disease after Bilateral Total Mastectomy: A Case Report.

ABSTRACT:

Introduction

Mammary Paget disease (MPD) and extramammary Paget disease (EMPD) are distinct conditions typically differentiated by anatomical location: MPD occurs on the breast and is indicative of underlying breast carcinoma, while EMPD arises in apocrine gland-rich areas like the genitals or axilla. MPD is almost always associated with underlying breast cancer, whereas EMPD may occur with or without malignancy. Both present as erythematous, scaly lesions with histopathologic features of Paget cells, necessitating clinicopathologic correlation for diagnosis.

Case presentation

We present a diagnostically challenging case of an erythematous, scaly plaque in the axilla of a 56-year-old female with a history of invasive ductal carcinoma and bilateral mastectomy. Initial finding

SUBMITTER: Ong MM 

PROVIDER: S-EPMC12659204 | biostudies-literature | 2025 Jan-Dec

REPOSITORIES: biostudies-literature