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ABSTRACT: Introduction
Toxic megacolon is a serious complication of ulcerative colitis (UC), characterized by marked colonic dilatation, abnormal bowel function, and systemic toxicity. Although toxic megacolon is rare in children and adolescents, it should remain in the differential diagnosis for acute severe UC in this group because delayed diagnosis and treatment can be fatal. The treatment for UC complicated by toxic megacolon is either immediate emergency surgery or short-term intensive drug therapy. If the latter does not result in significant improvement, emergency surgical intervention is necessary. Current treatment guidelines do not establish a standard medical approach for this condition.Case presentation
In this report, we describe an adolescent case of UC complicated by t
SUBMITTER: Kato M
PROVIDER: S-EPMC12659222 | biostudies-literature | 2025 Jan-Dec
REPOSITORIES: biostudies-literature