Research ethics and integrity challenges in accelerated clinical trials, an interview study.

ABSTRACT:

Background

Accelerated clinical trials for drugs and vaccines during global health crises allow for rapid access but pose research ethics and integrity challenges. Understanding these challenges is crucial for preserving research participants' safety and supporting research fairness and trustworthiness. This study aims to explore the research ethics and research integrity challenges associated with the acceleration of clinical trials.

Methods

This qualitative interview study used semi-structured online interviews with key stakeholders in the regulation, design, implementation, and publication of clinical trials as professionals (i.e. trial experts from academia, pharmaceutical companies, non-governmental organizations and national and international regulatory authorities and

SUBMITTER: Pallise Perello C 

PROVIDER: S-EPMC12659254 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature