Associations between breath acetone overnight dynamics and obstructive sleep apnea manifestations.

ABSTRACT:

Objective

Obstructive sleep apnea (OSA) is associated with metabolic dysregulation, potentially affecting ketone body metabolism. However, relationships between OSA and ketone body metabolism require further investigation. Thus, in this study, we investigated relationships between breath acetone levels and OSA manifestations (e.g., hypoxia and arousal events).

Methods

Baseline characteristics were collected from 66 eligible participants, and breath acetone levels were measured before and after polysomnography (PSG). Participants were categorized into two groups using the apnea-hypopnea index (AHI): normal-to-mild (< 15 events/h) and moderate-to-severe (≥ 15 events/h) OSA groups. Differences in baseline characteristics, PSG parameters, and breath acetone levels between the tw

SUBMITTER: Su YH 

PROVIDER: S-EPMC12659279 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature