Post-valvular energy exchange in bicuspid aortic valve with regurgitation and stenosis and its association with left ventricular workload: a 4D flow magnetic resonance imaging cross-sectional study.

ABSTRACT:

Background

Bicuspid aortic valve (BAV) regurgitation and stenosis considerably alter post-valvular flow dynamics and impose additional energetic load on the left ventricle (LV). We therefore sought to determine whether 4D Flow MRI-derived ascending-aortic kinetic energy (KE) and viscous energy loss (EL), can differentiate BAV subtypes and healthy controls, and are associated with LV remodeling markers.

Methods

Seventy-one participants (19 BAV without valve dysfunction, 17 with isolated aortic regurgitation (BAV-AR), 15 with isolated aortic stenosis (BAV-AS), and 20 healthy controls) underwent 3.0 T magnetic resonance imaging (MRI), including cine balanced SSFP and 4D-Flow. Post valvular KE, viscous EL, and the dimensionless EL index were computed from the 4D Flow velocity fi

SUBMITTER: Aliabadi S 

PROVIDER: S-EPMC12659313 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature