Synchronous Bilateral Breast Cancer with Heterogeneous Histology: Invasive Ductal and Lobular Carcinoma - A Case Report.

ABSTRACT:

Introduction

Synchronous bilateral breast cancer (SBBC) is rare, comprising 2-5% of all breast cancer cases. Even more uncommon is the presence of discordant histologies in each breast. This report discusses a case involving invasive ductal carcinoma (IDC) in the left breast and invasive lobular carcinoma (ILC) in the right breast.

Case presentation

A 46-year-old Arab woman presented with a 6-month history of a growing lump in the left breast and a newly noticed nodule in the right breast. Imaging and biopsy confirmed IDC (Grade 2, ER+/PR+/HER2-) in the left breast and ILC with LCIS in the right breast. Bilateral axillary lymphadenopathy was observed. She underwent neoadjuvant chemotherapy (doxorubicin/cyclophosphamide followed by paclitaxel), followed by a left radical mast

SUBMITTER: Al-Bitar A 

PROVIDER: S-EPMC12659413 | biostudies-literature | 2025 Jan-Dec

REPOSITORIES: biostudies-literature