Photoheterotrophic metabolism of acrylamide by a newly isolated strain of Rhodopseudomonas palustris.

ABSTRACT: Acrylamide, a neurotoxin and suspected carcinogen, is produced by industrial processes and during the heating of foods. In this study, the microbial diversity of acrylamide metabolism has been expanded through the isolation and characterization of a new strain of Rhodopseudomonas palustris capable of growth with acrylamide under photoheterotrophic conditions. The newly isolated strain grew rapidly with acrylamide under photoheterotrophic conditions (doubling time of 10 to 12 h) but poorly under anaerobic dark or aerobic conditions. Acrylamide was rapidly deamidated to acrylate by strain Ac1, and the subsequent degradation of acrylate was the rate-limiting reaction in cell growth. Acrylamide metabolism by succinate-grown cultures occurred only after a lag period, and the induction of acryla

SUBMITTER: Wampler DA 

PROVIDER: S-EPMC1265943 | biostudies-literature | 2005 Oct

REPOSITORIES: biostudies-literature