Prospective associations between nicotine type and the continuation of youth e-cigarette use.

ABSTRACT:

Background

E-cigarettes can contain either "tobacco derived" nicotine, which is comprised of almost entirely S-nicotine isomers, or "synthetic" nicotine, which is comprised of a mixture of R- and S-nicotine isomers ("R/S" nicotine). Emerging studies suggest R/S nicotine may be less pharmacologically potent, which could indicate a lower addictive potential. The purpose of the present study was to examine whether e-cigarette brands containing different nicotine types are associated with the continuation of youth's e-cigarette use.

Methods

Data came from a prospective cohort study of youth. Analyses were restricted to youth (ages 16-24; N = 216) who, at their baseline assessment in 2021, were using either JUUL (S-nicotine) or Puff Bar (R/S nicotine) e-cigarettes. Multivariable

SUBMITTER: Harrington T 

PROVIDER: S-EPMC12659524 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature