The reporting of health systems data use in primary results publications of clinical trials: a systematic review.

ABSTRACT:

Background

Data collected within clinical trials often overlaps with routinely collected Health Systems Data (HSD). There is potential for HSD to reduce burdens for trials and understanding HSD use can help triallists make decisions about using HSD in future trials. However, it is unknown to what extent HSD use has been reported in trial publications, despite the development of guidelines such as ESMO-GROW and CONSORT-ROUTINE extension for reporting HSD use in trials. This study expands on work previously conducted by Lensen and colleagues (Trials 21(1):398, 2020). It aims to provide insights into how HSD use is reported in main result publications that present main trial results, before and after the release of the CONSORT-ROUTINE extension.

Methods

This was a systematic re

SUBMITTER: Thompson J 

PROVIDER: S-EPMC12659570 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature