When Erectile Dysfunction Therapy Clouds the Vision: ST-BRVO after Sildenafil in a Healthy Male.

ABSTRACT:

Introduction

Sildenafil, a widely prescribed phosphodiesterase-5 (PDE5) inhibitor for erectile dysfunction, is generally well tolerated. However, ocular vascular complications - including non-arteritic anterior ischemic optic neuropathy, central serous chorioretinopathy, and retinal vein occlusion (RVO) - have been reported. Though rare, such events can occur even in individuals without conventional systemic risk factors.

Case presentation

A 55-year-old man with no prior medical history developed sudden, painless visual blurring in his right eye 48 h after ingesting a single 100 mg dose of sildenafil. Clinical evaluation revealed a superotemporal branch RVO with macular edema. A comprehensive systemic and hematologic workup, including thrombophilia screening and cardiac eval

SUBMITTER: Giri N 

PROVIDER: S-EPMC12659608 | biostudies-literature | 2025 Jan-Dec

REPOSITORIES: biostudies-literature