Small Desmoplastic Round Cell Tumor of the Kidney following Hodgkin Lymphoma: Case Report and Literature Review.

ABSTRACT:

Introduction

Desmoplastic small round cell tumor (DSRCT) is a rare and aggressive sarcoma that is most commonly present in males with abdominal and peritoneal invasion. There are potential curative therapeutic options, but survival remains poor. To this day, there have only been 22 reported cases of primary renal DSRCT in the literature and thoracic DSRCT has been rarely reported with very little known about effective therapy. This is the first reported case of renal DSRCT following a primary malignancy, and it is further distinguished by the application of whole-genome sequencing and targeted biological therapy.

Case presentation

The literature on renal DSRCT was reviewed, and we describe a patient with thoracic relapse of DSRCT following a primary renal lesion, initially t

SUBMITTER: Rosenfeld A 

PROVIDER: S-EPMC12659638 | biostudies-literature | 2025 Jan-Dec

REPOSITORIES: biostudies-literature