Identifying Patterns of Late Effects With Latent Class Analysis Among Adolescent and Young Adult Thyroid Cancer Survivors in California and Utah.

ABSTRACT:

Introduction

Thyroid cancer is one of the most common cancers in adolescents and young adults (AYA, 15 to 39 years), with an excellent 5-year survival of 98%. However, treatments for thyroid cancer such as radioactive iodine and thyroid hormone suppression may increase the risk for multiple late effects (LEs). We investigated the incidence of severe LE that clustered in AYA thyroid cancer survivors in a large population-based cohort.

Methods

California and Utah Cancer Registry records identified AYAs diagnosed with first thyroid cancer during 2006-2018 linked to statewide hospitalization, ambulatory surgery, and emergency department data. Cohort entry began 2 years from diagnosis. Severe LE included cardiovascular, respiratory, renal, and liver diseases, diabetes, and second

SUBMITTER: Ou JY 

PROVIDER: S-EPMC12659762 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature