Comparing efficacy and safety of mechanical thrombectomy in vertebrobasilar tandem occlusion versus isolated basilar artery occlusion stroke: A systematic review and meta-analysis.

ABSTRACT: BackgroundBasilar artery occlusion (BAO) is a rare stroke type, with subtypes like vertebrobasilar tandem occlusion (VBTO), complicating treatment. Mechanical thrombectomy (MT) is increasingly used, but evidence on its safety and effectiveness in VBTO compared to isolated BAO (iBAO) remains limited.MethodsPubMed, Cochrane Central, Embase, Web of Science, and ScienceDirect were searched till May 2025. The risk ratios (RR) were pooled along with 95% Confidence intervals (CI) under the random effects model using Review Manager. The Newcastle Ottawa Scale and GRADE assessment were used to assess the quality of studies and certainty of evidence. Successful recanalization was defined as a Thrombolysis in Cerebral Infarction (TICI) score of ≥2b. The modified Rankin Scale (mRS) is a scale used to

SUBMITTER: Waseem MH 

PROVIDER: S-EPMC12660123 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature