Preliminary analysis of gut microbiome characteristics in children with obstructive sleep apnea hypopnea syndrome.

ABSTRACT:

Objective

To analyze the characteristic changes in the gut microbiome in children with obstructive sleep apnea-hypopnea syndrome (OSAHS) and to investigate the relationship between the gut microbiome and polysomnography (PSG) results.

Methods

Children diagnosed with primary snoring and OSAHS by PSG were enrolled in the study group. Nonsnoring children undergoing elective surgery were selected as the control group. Stool, sleep monitoring data, and medical history data were collected. The clinical history data were analyzed by SPSS 25.0 software. 16S rRNA high-throughput sequencing technology was used to analyze the gut microbiome, and relevant biostatistical methods were used to analyze and describe the characteristics of the gut microbiome.

Results

A total of 62 OSAH

SUBMITTER: Wang Z 

PROVIDER: S-EPMC12660262 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature