GeneSeer: a sage for gene names and genomic resources.

ABSTRACT:

Background

Independent identification of genes in different organisms and assays has led to a multitude of names for each gene. This balkanization makes it difficult to use gene names to locate genomic resources, homologs in other species and relevant publications.

Methods

We solve the naming problem by collecting data from a variety of sources and building a name-translation database. We have also built a table of homologs across several model organisms: H. sapiens, M. musculus, R. norvegicus, D. melanogaster, C. elegans, S. cerevisiae, S. pombe and A. thaliana. This allows GeneSeer to draw phylogenetic trees and identify the closest homologs. This, in turn, allows the use of names from one species to identify homologous genes in another species. A website http://geneseer.c

SUBMITTER: Olson AJ 

PROVIDER: S-EPMC1266031 | biostudies-literature | 2005 Sep

REPOSITORIES: biostudies-literature