Prehospital plasma transfusion versus standard of care following traumatic injury: a review of the systematic reviews and a meta-analysis.

ABSTRACT:

Background

Individual studies suggest that administering prehospital blood products such as plasma to injured patients is feasible, may lower mortality, and improve coagulation. By compiling all existing evidence, we aimed to investigate whether prehospital plasma (PHP) transfusion can be safely administered and improve the clinical outcomes of trauma patients.

Methods

A systematic review (SR) and meta-analysis were conducted in accordance with the PRISMA guidelines to assess the effectiveness and safety of PHP transfusion compared to the standard of care in trauma patients. A literature search (2012 and 2024) was performed in PubMed, MEDLINE, EMBASE, and the Cochrane Library using the terms: "plasma resuscitation," "prehospital plasma," "prehospital blood components," "emer

SUBMITTER: El-Menyar A 

PROVIDER: S-EPMC12660323 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature