Risk factors associated with severe RSV disease among hospitalized children in the second year of life: a multicenter study.

ABSTRACT:

Purpose

The second year of life is gaining increased attention in the era of long-acting RSV immunoprophylaxis. This multicenter study, across pre- and post-COVID seasons, aimed to assess the association between specific key risk-factors and severe RSV-related disease among hospitalized children aged 12-23 months.

Methods

This retrospective study included children aged 12-23 months hospitalized with RSV across 11 medical-centers (2017-2021). We compared outcomes of prolonged hospitalization (> 3 days) and PICU (Pediatric Intensive Care Unit) admission for children with risk factors (prematurity < 37 weeks, major congenital heart disease (CHD), chronic lung disease of prematurity (CLD) or Down syndrome (DS)) and those without the respective risk factor, adjusting for demograp

SUBMITTER: Domany KA 

PROVIDER: S-EPMC12660361 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature