Postprandial glycemic response in different ethnic groups in East London and its association with vitamin D status: Study protocol for an acute randomized crossover trial.

ABSTRACT: BackgroundIn the UK, Black African-Caribbeans (ACs) and South Asians (SAs) have 3-6 times greater risks of developing type-2 diabetes mellitus (T2DM) and significantly higher prevalence of vitamin D (vitD) deficiency than White Caucasians. East London is among the areas with the highest prevalence of T2DM and the highest proportion of ethnic minority groups. This ethnic health inequality is ascribed to socioeconomic standing, dietary habits, culture, and attitudes, while biological diversity has rarely been investigated.AimThe study aims to investigate the difference in the postprandial glycemic response (PGR), an independent risk factor of T2DM, between ethnic groups (White Caucasians, SAs, and ACs) in East London and its association with vitD status.MethodsThis acute randomized crossover

SUBMITTER: Dong H 

PROVIDER: S-EPMC12660509 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature