Impact of treatment modality on survival in FIGO stage IIB cervical cancer: a population-based propensity-score matched analysis.

ABSTRACT: To investigate the impact of treatment modality on survival of International Federation of Gynecology and Obstetrics (FIGO) stage IIB cervical cancer. Patients with FIGO stage IIB cervical cancer registered in the Surveillance, Epidemiology, and End Results database between 1988 and 2015 were identified and grouped according to their treatment modalities. Propensity score matching (PSM) was performed to adjust the baseline characteristics. A total of 4718 stage IIB patients with eligible data were identified. Of them, 902 underwent surgery and 3816 received chemoradiotherapy alone. After PSM, 1208 patients were paired without baseline difference. Patients undergoing surgery (n = 604) had significantly improved overall survival (OS, 5-year rate: 68.0%, P = 0.007) and cancer-specific surviva

SUBMITTER: Tu H 

PROVIDER: S-EPMC12660729 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature