Flexible time-restricted eating combined with exercise in a free-living setting for middle-aged women with overweight/obesity: a randomized controlled trial.

ABSTRACT: Obesity poses a significant public health challenge among middle-aged women, driven by physiological changes associated with aging and menopause. This parallel-group, assessor-blinded, four-arm randomized controlled trial investigated the effects of 12-week 8-hour flexible time-restricted eating (flexTRE) and aerobic exercise (EX), alone or in combination (flexTRE+EX), on body composition and metabolic health in a free-living setting. Participant enrolment began on September 1^st 2023 and data collection was completed on July 1^st 2024. Conducted at a single research site in Hong Kong, the trial enrolled women aged 40-60 years with overweight/obesity. Participants were randomized in a 1:1:1:1 ratio to a flexTRE, EX, flexTRE+EX, or control (CON) group (n = 26 per group),

SUBMITTER: Dai Z 

PROVIDER: S-EPMC12660762 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature