Expression of cytochrome P450 monooxygenase genes in pyrethroid-resistant Aedes albopictus.

ABSTRACT: Control of dengue vectors with synthetic pyrethroids is employed worldwide but development of pyrethroid resistance in Aedes mosquitoes is a big challenge for successful prevention of dengue. Pyrethroids are of two types: type I (devoid of α-cyano group) and type II (contain α-cyano group) which differ in their toxic effect. Therefore, this study investigated potential difference in the cytochrome P450 monooxygenase (CYP) mediated resistance status against two types of synthetic pyrethroids in wild Aedes (Ae.) albopictus populations from dengue endemic sub-Himalayan West Bengal. The role of CYPs in resistance development was studied through synergist assay and gene expression studies. Widespread resistance was observed against permethrin (type I) and lambdacyhalothrin (type II) in studied

SUBMITTER: Das P 

PROVIDER: S-EPMC12660890 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature