NMR and GC-MS based metabolic profiling, total phenolic content, antibacterial, antioxidant, anticancer and In-silico antiviral activity of Origanum ramonense plant.

ABSTRACT: Origanum ramonense is a rare and underexplored aromatic (Lamiaceae family) native to the Mediterranean region, but despite its prospects as a medicinal plant, there is a shortage of spectrometry based metabolic profiling of this plant. Thus, the objective of this study was to carry out a detailed investigation of the metabolic profile of Origanum ramonense extracts using multiple solvents (methanol, methanol/water, ethyl acetate, dichloromethane/methanol, and hot water) of varying polarity, and further assess its bioactive potential. Using analytical tools such as NMR and GC/MS, we identified functional groups of plant metabolites and further employed multiple assays such as DPPH (antioxidant activity) and the Folin-Ciocalteu method to understand the plant's bioactivity. The extracts were

SUBMITTER: Dutta A 

PROVIDER: S-EPMC12660920 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature