Development and validation of a clinical risk score nomogram for distinguishing nontuberculous mycobacteria from Mycobacterium tuberculosis pulmonary disease.

ABSTRACT:

Background

The prevalence of nontuberculous mycobacterial pulmonary disease (NTM-PD) has increased substantially in recent years, positioning it as a major global public health concern. This rise is compounded by its clinical and radiographic similarities to pulmonary tuberculosis (PTB), encompassing shared manifestations such as chronic cough, hemoptysis, and cavitary lesions on imaging, which pose significant challenges in differentiating infections caused by nontuberculous mycobacteria from those attributable to Mycobacterium tuberculosis. As a result, NTM-PD is frequently misdiagnosed as PTB, prompting the administration of antituberculous regimens that are ineffective against Mycobacterium tuberculosis (NTM) species and may foster antimicrobial resistance. These diagnostic err

SUBMITTER: Wen L 

PROVIDER: S-EPMC12661112 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature