Switch-Off response to mid-cingulate cortex stimulation: a video case report.

ABSTRACT:

Background

Electrical cortical stimulation (ECS) is commonly used during invasive presurgical evaluation of drug-resistant focal epilepsy for functional mapping and delineation of the epileptogenic zone.

Case presentation

A 31-year-old woman underwent stereo-EEG evaluation for presurgical assessment of drug-resistant focal epilepsy, likely left frontal or multifocal. During 50 Hz ECS of the right mid-cingulate cortex, a reproducible behavioural response was observed, characterised by left ear popping, head drop, eye closure, and speech/motor arrest, without loss of awareness. This semiology differed from her habitual seizures, and the region was not considered part of the presumed epileptogenic zone.

Conclusion

This case represents a rare video-documentation of stimul

SUBMITTER: Vassallo P 

PROVIDER: S-EPMC12661145 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature